VCVITAMINS/CHART

The Bottom Line

Yes, you can safely combine ginger and ginkgo biloba; no significant interaction exists between these two supplements.

VERDICT

Ginger and Ginkgo Biloba together are safe for healthy adults. The two supplements work through different biological pathways, and no significant interaction has been reported. You can combine them without special timing or spacing.

Safe to combine Moderate evidence
01 / MECHANISM

How They Interact

Ginger's primary active compounds, gingerols and shogaols, exert their effects by inhibiting COX enzymes and reducing inflammatory prostaglandin synthesis, while also mildly reducing platelet aggregation by interfering with thromboxane A2. Ginkgo biloba's ginkgolides, particularly ginkgolide B, act as antagonists of platelet-activating factor, a separate pathway for platelet clumping. Because these two mechanisms do not involve the same enzymes, receptors, or cytochrome P450 isozymes at typical doses, combining them does not create a synergistic or antagonistic interaction. Additionally, neither compound significantly alters the absorption or metabolism of the other, so you do not need to space them apart.

02 / BEST PRACTICES

How To Take Them

Take ginger and ginkgo together in the morning with a meal to avoid potential stomach irritation and to keep ginkgo's mild stimulatory effect from interfering with sleep. There is no required spacing between the two; taking them at the same time is fine. If you take ginkgo for memory or circulation, aim for 120 mg standardized extract in two divided doses (60 mg morning and midday), and for ginger use 250–500 mg of standardized extract or 1–2 grams of fresh root per day for general anti-inflammatory benefits. If you miss a dose, simply take it at the next meal and don't double up. Combining both with a fat-containing meal may mildly enhance absorption of their fat-soluble constituents.

03 / FORM MATTERS

Form & Quality Differences

Standardized ginger extract (typically 5% gingerols) and ginkgo biloba leaf extract (standardized to 24% flavone glycosides and 6% terpene lactones) are the forms most often studied. Fresh ginger root and ginkgo teas are more variable and the active compound concentrations are lower, so interaction risk remains minimal but dose is less consistent. If you take ginger powder capsules, check the gingerol percentage to match clinical study doses.

05

Practical Tips

06

Frequently Asked Questions

Who Should Be Careful People on anticoagulant or antiplatelet medications should talk to their doctor before adding ginger or ginkgo, since both can increase bleeding risk. Pregnant individuals should avoid ginkgo, and ginger should be limited to culinary amounts (under 1 gram per day) during pregnancy. Individuals with gallstones or bile duct obstruction should avoid high doses of ginger. Ginkgo is also not recommended for people with epilepsy, because it may increase seizure risk.
08

Sources & Further Reading

  1. NIH ODS NIH Office of Dietary Supplements — Ginger Fact Sheet
  2. NIH ODS NIH Office of Dietary Supplements — Ginkgo Biloba Fact Sheet
  3. Examine.com Examine.com — Ginger interaction page
  4. Examine.com Examine.com — Ginkgo Biloba interaction page

Reviewed by Caroline M. on April 10, 2025 for accuracy against the sources listed above. This page is educational and is not a substitute for professional medical advice.

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